Publication
Effective Management of Refractory Postcardiotomy Bleeding With the Use of Recombinant Activated Factor VII
Farzan Filsoufi, Javier G. Castillo, Parwis B. Rahmanian, Corey Scurlock, Gregory Fischer, David H. Adams
Severe coagulopathy after cardiovascular surgery may lead to intractable bleeding and is associated with increased mortality and morbidity. Recent studies have suggested that recombinant activated factor VII (rFVIIa) may play a role in decreasing postoperative bleeding. ... This study suggests that rFVIIa is safe and efficacious in the management of refractory postcardiotomy bleeding. The use of rFVIIa is associated with reduced blood loss, rapid improvement of coagulation variables, and decreased need for blood products.
Page Created: January 08, 2018
Last Updated: January 08, 2018
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