Publication
Procedures and Outcomes of Surgical Aortic Valve Replacement in Adults
Amine Mazine, MD, Ismail El-Hamamsy, MD
The ideal aortic valve substitute remains elusive. Bioprosthetic valves are the replacement option of choice in elderly patients undergoing aortic valve replacement (AVR). When implanted in young and middle-aged adults, both bioprosthetic and mechanical valves are associated with excess mortality compared with the age- and sex-matched general population. The Ross procedure is the only operation that can restore normal life expectancy in young and middle-aged adults undergoing AVR. In this article, the authors review the various options for surgical AVR and examine their contemporary applications and outcomes.
Key points
- Although in elderly patients, bioprosthetic valves are durable and associated with low rates of valve-related complications, in non-elderly adults, they are associated with reduced durability and lower than expected survival, both of which are worsened by the presence of patient-prosthesis mismatch.
- In young adults, mechanical valves are associated with lower rates of prosthesis degeneration and need for reoperation compared with bioprosthetic valves, at the cost of higher rates of anticoagulation-related bleeding and thromboembolic events.
- Nevertheless, both mechanical and bioprosthetic valves are associated with excess mortality compared with the general population when implanted in non-elderly patients.
- The Ross procedure is the only operation that can restore a normal life expectancy in young and middle-aged adults undergoing aortic valve replacement.
Page Created: March 18, 2021
Last Updated: March 24, 2021
Share
Publications
-
2-Year Clinical and Echocardiography Follow-Up of Transcatheter Mitral Valve Replacement With the Transapical Intrepid System
Vinayak Bapat, Eric Weiss, Sean Pinney, David H Adams, Angie Zhang , Michael Mack, Martin B Leon, et al. -
Optimal timing of Ross operation in children: A moving target?
Igor E Konstantinov, Emile Bacha, David Barron, Tirone David, Joseph Dearani, Yves d'Udekem, Ismail El-Hamamsy, Hani K Najm, Pedro J Del Nido, Christian Pizarro, Peter Skillington, Vaughn A Starnes, David Winlaw -
Mitral Valve Intervention in Elderly or High-Risk Patients: A Review of Current Surgical and Interventional Management
Maheedhar Gedela, Busra Cangut, Lucy Safi, Parasuram Krishnamoorthy, Dimosthenis Pandis, Ahmed El-Eshmawi, Gilbert H L Tang -
Total artificial heart implantation as a bridge to transplantation in the United States
Shinobu Itagaki, Nana Toyoda, Natalia Egorova, Erick Sun, Timothy Lee, Percy Boateng, Gregory Gibson, Noah Moss, Donna Mancini, David H Adams, Anelechi C Anyanwu